Good morning and welcome to our coverage of the Amanda Knox appeal hearing. Our reporter Rosa Silverman is in Perugia ready to bring you all the details from the court.
Knox's lawyer, Luciano Ghirga, is due to speak first. The case is due to start 9am but there are suggestions it won't
Here's how today will pan out: Knox and her former lover, Raffaele Sollecito, 27, will deliver final statements in a last-ditch attempt to persuade the court that they had nothing to do with the murder of Knox's then-flatmate. The judges and jury will then retire to consider whether to acquit the pair, uphold the convictions or - as prosecutors have requested - even increase their sentences.
The hearing has started. We're hearing the open speech from Knox's lawyer.
The process is expected to reach its climax today - and we look set for a long night. Unlike British courts, the jury must stay in chambers until a verdict is reached.
Knox's Italian lawyer is delivering a passionate speech - he's currently painting Rudy Guede as unreliable and a liar. Guede - an Ivory Coast national convicted of murdering Meredith Kercher - has given evidence for the prosecution containing an direct accusation against Knox and Sollecito
The defence claims the murder weapon was not the large knife featured in the prosecution's case - Knox's lawyer claims a third knife was used to kill Meredith Kercher
Knox's lawyer: Defendants should only be convicted if they are guilty beyond reasonable doubt
Rafaele Sollecito is giving evidence. He says he's very tense.
Sollecito: "I want to communicate what I'm going through and what I'm suffering but it's impossible for me to do that in a few minutes."
"I have never hurt anybody - never in my life."
Sollecito says he feels like he's living in a nightmare and cannot wake up
Sollecito: "Every day I spend in jail - every day is like a death itself."
Sollecito, dressed in an open-necked shirt, proceeds with his statement. He again denies knowing Rudy Guede.
Sollecito says he and Knox have now spent more than 1,400 days in jail, living in a space of 2m by 3m.
There is a lot of comment about the case on the social media networks - much of which can't be repeated. We'll be curating some of those that can to give a flavour of the public reaction to what's happening
Sollecito now recalls the days preceding the murder, saying he was happy and content having just met a "very sweet girl": Knox. "That was the first weekend we were meant to spend together."
Sollecito says he and Knox had planned to spend the night of the murder together. He says: "It was our desire to leave the world outside and spend the night together."
"I have nothing more to say as I believe the rest would be superfluous," continues Sollecito, but not before removing a bracelet inscribed with the words "Raffaele and Amanda free". He says: "I would like this bracelet to belong to history and the past ... there will be a new future for us, one which I think we deserve."
Here's Knox. She takes to the stand and address the court in Italian.
Knox steadies herself after a weepy start before continuing.
"I lost a friend in the most brutal way," says Knox, referring to Kercher.
Knox looks scared and intimidated in a packed courtroom
Knox: "Four years ago I did not know what tragedy was, it was something that belonged on television."
Knox tells the court if she had been there that night she would have been dead too
Knox reiterates her claim that she was not present when Meredith Kercher died
Knox's voice is the point of breaking, but she continues, claiming she had been manipulated.
A series of denials follows: I have not killed, I have not raped, I was not present at the scene of the crime.
Like Sollecito, Knox denies ever knowing Rudy Guede, the other man convicted of Miss Kercher's murder in a separate trial.
Knox says she just wants justice for her friend, Meredith Kercher.
Knox concludes by saying that she and Sollecito do not deserve to be punished for something they didn't do. She thanks the court before sitting down.
The judge tells the packed court room 'this is not a football match' and asks everyone to respect the jury's verdict when it comes
So that's that. A few words follow from the judge who explains that he, his fellow judges and the jury will now retire to consider their verdict. He estimates they will return to the court at around 8pm local time.